Nicolas Le Novère studied molecular biology and biochemistry at École Normale Supérieure, evolution at University Paris XI, biophysics and pharmacology at Paris VI. After a PhD thesis on the structure and function of neuronal nicotinic receptors with Jean-Pierre Changeux at the Pasteur Institute, that comprised experimental and bioinformatics analyses, he pursued a post-doctoral training in modelling bacterial chemotaxis with Dennis Bray at the University of Cambridge (UK). At that time, he was privileged to participate to the development of what was becoming a new field in life sciences, systems biology. As group leader at the EMBL-European Bioinformatics Institute, he merged his two main scientific interests, computational systems biology and the study of neuronal function. Nicolas Le Novère is now group leader at the Babraham Institute. Besides his research on cellular signalling, Le Novère develops resources for systems biology, for instance standards like SBML and SBGN or databases like BioModels Database. Le Novère is also visiting group leader at EMBL-EBI, and directeur de recherche at the French Centre National de la Recherche Scientifique (CNRS).