File:Bohr effect.png

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Summary

Description
English: First description of the Bohr effect, upon which pH affects binding of oxygen by hemoglobin. This is also one of the first example of cooperative binding. X-axis: oxygen partial pressure in mmHg, y-axis % oxy-hemoglobin. The measurements were made with freshly obtained dog blood, except for the top curve, which represents horse blood.
Date
Source Bohr, C., Hasselbalch, K., and Krogh, A. (1904) Ueber einen in biologischer Beziehung wichtigen Einfluss, den die Kohlensäurespannung des Blutes auf dessen Sauerstoffbindung übt. Skandinavisches Archiv Für Physiologie, 16(2): 402-412. doi:10.1111/j.1748-1716.1904.tb01382.x.
A rough translation into English is available here (WebCite copy).
Author Christian Bohr
Other versions

Republished in
Stefan MI, Le Novère N (2013) Cooperative Binding. PLoS Comput Biol 9(6): e1003106. doi:10.1371/journal.pcbi.1003106

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